Packing

10g/bottle

Storage

GLPG1690 inhibits ATX-induced LPA 18:2 production in mouse, rat, and healthy donor plasma in a concentration-dependent manner, with IC₅₀values of 418 nM, 542 nM, and 242 nM, respectively. GLPG1690 displays improved pharmacokinetic properties, with a low plasma clearance and high bioavailability in mouse and rat. The good pharmacokinetic profile is further confirmed in dog, with GLPG1690 showing low plasma clearance (0.12 L/h/kg) and a high bioavailability (63%)^[1].

Appearance

Pale powder 

                         1 H-NMR Identification

In accordance with the standard 

Purity (By HPLC) 

≧98%

Storage

-5~20℃, cool and dry place, sealed.